We are in constant pursuit of breakthroughs that change patients' lives. We innovate each day to make the world a better place. It was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more creative, attract and retain the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and demonstrates our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and represents the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We embody our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, using digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.