We are in relentless pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more creative, attract and retain the best people, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and embodies the value we work to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.