We're in constant pursuit of breakthroughs that change patients' lives. We innovate each day to make the world a more healthy place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more creative, attract and retain the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and represents the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We fulfill our purpose by seeking the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, using digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.