We are in constant pursuit of breakthroughs that transform patients' lives. We drive innovation daily to make the world a more healthy place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more innovative, attract and retain the best talent, and know how to harness the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and embodies the value we strive to bring to patients and society. Our purpose makes certain that patients stay at the heart of all we do. We fulfill our purpose by seeking the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.