We are in tireless pursuit of breakthroughs that transform patients' lives. We innovate each day to make the world a better place. This was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what we instinctively know: that purpose-driven companies deliver better results, are more innovative, recruit and maintain the best professionals, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and represents the value we aim to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We embody our purpose by finding the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.