We are in constant pursuit of breakthroughs that change patients' lives. We create innovations every day to make the world a better place. It was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more inventive, attract and retain the best professionals, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We embody our purpose by sourcing the best science in the world, working with others in the healthcare system to improve access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and driving the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.